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Plasma miR-34a-5p outperforms miR-126-3p in predicting cognitive decline in cerebral small vessel disease patients with impaired glucose regulation.
Yanan Wang, Baoying Sun et al.
Plasma miR-34a-5p demonstrates superior diagnostic and predictive performance for cognitive decline in cerebral small vessel disease patients with impaired glucose regulation compared to miR-126-3p, potentially mediating the effect of impaired glucose regulation on cognitive dysfunction through apoptosis, oxidative stress, and synaptic function pathways.