Mingxu Chen, Xinzheng Wei et al.
Adding Guipiheji to ferrous succinate significantly improved hematologic and iron metabolism outcomes in IDA patients compared to ferrous succinate alone, with comparable safety.
Kai Gao, Wei Zhang et al.
Ecliptasaponin A alleviates inflammation and fibrosis in experimental MASH mice by targeting both the NLRP3 inflammasome and YAP signaling pathway, showing dose-dependent therapeutic effects.
Katie Lawther, Nicholas J Dimonaco et al.
Supplementation of *Asparagopsis taxiformis* (ASP) to dairy cows reduced methane yield by 54% and modulated the rumen microbiome by increasing gene abundance for pyruvate and propionate production pathways, decreasing those for acetate and methane, and altering the distribution of methane-related functions across a broader range of taxa.
Nikhil A Nandkumar, Aruna Chakrala
H. pylori eradication in a menstruating woman with iron deficiency anemia led to symptom resolution and improvement in iron parameters, highlighting the importance of considering H. pylori in unexplained IDA.
Lydia Okyere, Angela Di Fulvio et al.
Long-term culture of germ-free zebrafish using gamma-irradiated diets resulted in smaller size, lower weight, and aberrant gene expression in immune response, metabolism, and development pathways compared to conventionally reared zebrafish.
Guoqiang Huo, Xuan Liu et al.
Maternal dietary taurine supplementation (0.1–0.2%) during gestation significantly increases offspring body weight and improves intestinal health in 15-day-old lambs by enhancing the intestinal barrier, reducing inflammation, and modulating gut microbiota toward beneficial taxa like Ruminococcus and Eubacterium.
Pieter Van den Abbeele, Lam Dai Vu et al.
Yeast protein (YP) modulated gut microbiota metabolites in older male adults ex vivo, enhancing gut barrier function and reducing inflammation, with comparable or superior effects to whey and soy protein isolates in some aspects, including lower gas production and TMAO levels.
Chaoyu Wu, Songmao Ouyang et al.
Continuous probiotic supplementation significantly reduced intestinal hyperpermeability, attenuated hepatic damage, decreased systemic inflammation, and improved survival in a d-galactosamine/lipopolysaccharide (GalN/LPS)-induced fulminant liver failure (FLF) rat model.
Urszula Krupa-Kozak, Agnieszka Owczarczyk-Saczonek et al.
This study is a protocol for a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effect of 8-week chicory-derived inulin-type β-fructans (ITFs) supplementation on health parameters in mild psoriasis patients, with the primary outcome being the change in PASI score from baseline to 8 weeks.
Omar Lweno, Victoria S Reynolds et al.
This study protocol describes a controlled feeding trial designed to determine the optimal vitamin B12 dosage for pregnant women by evaluating the pharmacokinetics and status indicators of 2.6 µg, 10 µg, and 50 µg daily doses compared to non-pregnant controls.
Shonaz Ahmadikhatir, Pardis Irandoost et al.
This randomized, double-blind clinical trial aims to investigate the effect of high-protein (1.6 g/kg/day) enteral nutrition compared to conventional-protein (1.2 g/kg/day) enteral nutrition on intestinal permeability, measured by changes in serum Zonulin levels, in 88 critically ill ICU patients over 10 days.
Branka Djordjevic, Vladana Stojiljkovic et al.
Glutamine supplementation shows potential benefits for intestinal integrity, oxidative stress, muscle damage biomarkers, immune function, and inflammation in both preclinical and clinical studies, but findings are inconsistent, and routine use for performance enhancement is not currently justified.
Michiaki Abe, Kazuhiko Kawaguchi et al.
Potassium citrate/sodium citrate (PCSC) supplementation in rats significantly increased vastus lateralis muscle mass relative to body weight and enhanced renal function maturation, with specific metabolic changes observed in both tissues.
Jie Zhang, Ying Wei et al.
Gurigumu-13 (GR) ameliorates non-alcoholic fatty liver disease (NAFLD) by modulating key targets like STAT3 and pathways such as PI3K/AKT/mTOR, thereby regulating lipid metabolism, alleviating oxidative stress, and improving insulin resistance.
Xinyu Gong, Xue Wang et al.
Pretreatment with *Pediococcus acidilactici* M22 significantly alleviated clinical symptoms, reduced inflammation and oxidative stress, preserved intestinal barrier integrity, and mitigated gut microbiota dysbiosis in C57BL/6 mice infected with *E. coli* O157:H7.
Maryam Nasri, Nejat Mahdieh et al.
A novel likely pathogenic ACADSB variant (c.907G > C; p.G303R) was identified in an asymptomatic Iranian infant diagnosed with 2-Methylbutyryl-CoA dehydrogenase deficiency through newborn screening, enabling presymptomatic management and prevention of complications.
Zhiwu Dong, Keliang Huang et al.
Alisol F 24-acetate (ALI) suppressed macrophage pyroptosis by targeting the KEAP1/NRF2 pathway, thereby demonstrating a protective mechanism against metabolic dysfunction-associated steatohepatitis (MASH) as a natural antioxidant.
Yibin Xu, Yujie Huang et al.
Maternal supplementation of 400 mg/kg curcumin alleviates E. coli-induced intestinal inflammation and growth depression in offspring by strengthening the mucosal barrier, enhancing antioxidant status, and modulating gut microbiota, specifically by increasing Lactobacillus and reducing Barnesiella.
Hamidreza Mazangi, Negar Panahi et al.
The Quercetin-loaded avocado oil nanoemulsion (NAOQu) significantly reverses high-fat diet-induced testicular dysfunction and metabolic stress by increasing testosterone levels by 85%, reducing oxidative damage, and downregulating hypothalamic NPY mRNA expression.
Corina-Aurelia Zugravu, Marta Petre et al.
Ageing increases vulnerability to thyroid dysfunction through a U-shaped relationship with iodine intake, where older adults exhibit a diminished ability to escape the Wolff–Chaikoff effect and are further influenced by age-related declines in renal clearance, gut microbiota diversity, and nutrient co-factors.
Marek Pieszka, Kinga Szczepanik et al.
Colostrum supplementation significantly improved growth performance and feed conversion ratio in weaned piglets by enhancing intestinal barrier function, nutrient absorption, and digestive enzyme activity.
Mina Marie Minge, Christine Henriksen et al.
The 7209 L whole-room indirect calorimeter is technically valid and reproducible for measuring VO2, VCO2, and postprandial energy expenditure, but shows lower reproducibility for RER and TEF, with a substantial minimal detectable change for TEF (43.76%).
Hyunjun Choi, Zixiao Deng et al.
Increasing soybean meal in low-cost diets negatively impacted pig growth and nutrient digestibility, but β-mannanase supplementation mitigated these effects by improving digestibility and early-phase growth.
Katrin A Böckmann, Wolfgang Bernhard et al.
Choline chloride, choline bitartrate, GPC, and egg-PC similarly increase plasma choline concentrations after 48 hours of supplementation in preterm infants, with GPC showing a faster initial increase.
Max T Deutz, Andrew T Askow et al.
Multienzyme supplementation in middle-aged and older adults resulted in a faster time to peak plasma leucine concentrations and elevated postprandial plasma glucose and total NEFA concentrations, suggesting improved macronutrient digestion.
Lili Jiang, Qingmei Wang et al.
Sequential enteral nutrition support, compared to routine enteral nutrition, significantly improved nutritional status, immune function, neurological impairment, daily living ability, and reduced gastrointestinal dysfunction and complications in elderly patients with severe ischemic stroke after thrombectomy within 14 days post-intervention.
Robin P da Silva, Brandon J Eudy
A common dysregulation in folate metabolism and consequent metabolic disturbances, along with shared transcriptional profiles involving STAT5b, AhR, and ARNT, were identified in methionine and choline deficient (MCD) and glycine N-methyltransferase knockout (GNMTKO) mouse models of liver fibrosis.
Guilherme Henrique Gebim Polizel, Ángela Cánovas et al.
Prenatal nutritional strategies in Nellore cattle differentially influenced long-term transcriptomic-metabolomic interactions in skeletal muscle, meat, and subcutaneous fat, with the mineral-only control (NP) group showing the highest number of pathways exclusively enriched for lipid metabolism and protein metabolism, while protein-energy supplemented groups (PP and FP) were more associated with immune function, stress resilience, and nutrient delivery.
Helena Nti, Paul D Hastings et al.
Early-life small-quantity lipid-based nutrient supplements (SQ-LNS) did not significantly affect hair cortisol concentration (HCC) in children aged 9-11 years overall, but did significantly reduce HCC in children whose mothers had 0-5 years of schooling compared to non-LNS groups.
Renuka Agarwal, Anne E Curé et al.
Asymmetries in the fitness effects of traded resources significantly influence mutualist persistence and trait evolution, with more vulnerable mutualists (AdeOP strains) showing higher extinction rates under obligate conditions, and evolutionary changes in resource overproduction and resource use efficiency differing across environments.
Feng Xiang, Zhiqiang He et al.
Xiasangju (XSJ) ameliorates liver injury, lipid accumulation, inflammation, oxidative stress, and fibrosis in a metabolic dysfunction-associated steatohepatitis (MASH) mouse model by modulating key metabolic pathways and inhibiting the TGF-β1/Smads and PI3K/AKT/Hmox1 signaling pathways.
Emmanuel Somm, Elodie Perroud et al.
IL-18BP deficiency exacerbates diet-induced liver damage, inflammation, and fibrosis in mice by reducing intestinal antimicrobial peptide production and altering gut microbiota composition.
Chia Juan Lim, Jue Ying Wong et al.
Dietary supplementation with choline propionate significantly enhances egg production, egg quality, and liver health in laying hens, matching or surpassing choline chloride in reducing fatty liver incidence and exhibiting a mild methionine-sparing effect.
Nghia Duc Nguyen, Hop Xuan Nguyen et al.
Continuous supplementation with 360 µg/day of Vitamin K2 (MK-7) was associated with a progressively greater height gain over time (interaction β = 0.05 cm/month), with the most significant effects observed in pre-pubertal boys.
Lucrezia Forte, Nives Parabita et al.
Dietary polyphenols are extensively metabolized in dairy cows, with some derivatives like isoflavones, phenyl-γ-valerolactones, urolithins, and hippuric acid being transferred into milk at low concentrations, influencing milk's antioxidant capacity and fatty acid profile.
En Liu, Shujun Sun et al.
Small peptide supplementation enhances growth performance and rumen function in finishing beef cattle by modulating ruminal microbial communities and epithelial gene expression, leading to improved feed efficiency and nitrogen utilization.
Adriana Monserrath Orellana-Paucar, Erick Thomas Mosquera-Lopez et al.
Co-administration of folic acid with phenytoin may be beneficial for preventing folate deficiency without significantly altering phenytoin pharmacokinetics, while avoiding noni juice is advisable due to moderate evidence from a case report, and evidence regarding other food interactions and piperine is contradictory or inconclusive, necessitating further rigorous research.
Lola Bosc, Thomas Sécher et al.
The pseudopaline-dependent Cnt pathway is essential for *P. aeruginosa* to acquire zinc under severe zinc-limiting conditions, and its absence leads to impaired biofilm formation, reduced antibiotic tolerance, altered macrophage interactions, and attenuated virulence in a mouse lung infection model.
Katharina Feil, Daniela Schweikert et al.
A standardized, interdisciplinary protocol for implementing the ketogenic diet (KD) in adult ICU patients with refractory and super-refractory status epilepticus (RSE and SRSE) is presented, advocating for early initiation in SRSE patients without contraindications due to its safety, reversibility, and rapid implementability.
Haodong Wang, Zhi Lu et al.
Dietary lycopene alleviates cadmium-induced renal injury in broilers by modulating mitochondrial quality control pathways, thereby maintaining mitochondrial structural and functional integrity.
Atsushi Miura, Shiori Ikeda et al.
Hepatic fibrogenesis in MASH is driven by an elevated SAM/SAH ratio that induces epigenetic remodeling via specific histone H3 modifications (increased H3K4me3/H3K9me3 and decreased H3K27me3), a process that can be attenuated by inhibiting methionine adenosyltransferase.
Libor Závorka, Johan Höjesjö et al.
Dietary n-3 LC-PUFA deficiency in juvenile salmonids reduced brain n-3 LC-PUFA content, leading to reduced competitiveness, suboptimal habitat use, and slower growth, suggesting impaired behavioral flexibility and fitness in changing ecosystems.
Joanna Tokarczyk, Agnieszka Jaworowska et al.
A high-fiber diet significantly reduced zinc bioaccessibility from dietary supplements, with bioaccessibility being highly dependent on the chemical form of zinc, with Zn picolinate showing superior bioaccessibility and less interaction with food components.
Akira Kado, Kazuya Okushin et al.
IL-10 treatment attenuates lipotoxic injury and improves metabolic dysfunction-associated steatotic liver disease (MASLD) phenotypes by reducing hepatic lipid accumulation, oxidative stress, and apoptosis, while promoting glucose metabolism and suppressing insulin resistance, primarily through STAT3/AKT/mTOR signaling pathways.
Lea Pueschel, Stefanie Claire Fuhrberg et al.
The German version of the Nine Item Avoidant/Restrictive Food Intake disorder screen (NIAS) is a reliable screening instrument for ARFID in German-speaking IBD patients, with women scoring significantly higher than men.
Lijuan Qi, Junyu Ning et al.
D-allulose demonstrated good gastrointestinal tolerance in healthy Chinese adults over 30 days, with mild, transient symptoms and no dose-dependent differences, while systemic safety indicators remained normal, though high-dose intake significantly reduced BMD T-scores in participants aged 35 years and older.
Dilip Kumar Kandar, Keshavi Killi et al.
A multipronged outpatient approach combining targeted antimicrobial therapy, bioactive collagen–nanosilver wound dressings, nutritional optimization, and patient/caregiver education achieved full healing of chronic, infected venous ulcers, reducing the need for inpatient care.
Hao Xie, Zhichao Gao et al.
The age-dependent decline of Ubc9-mediated SUMOylation promotes hepatocyte senescence and liver dysfunction by allowing non-SUMOylated RPL3 to translocate into the nucleus and activate the DHX9-p16 axis.
Chad Kerksick, Drew Gonzalez et al.
Creatine monohydrate supplementation is a safe and effective ergogenic aid that significantly enhances muscular strength by approximately 8%, increases fat-free mass, improves high-intensity sprint performance, and accelerates functional recovery across athletic and tactical populations.
Hojjat Seraji-Kopkan, Seyyed Javad Hosseini-Vashan et al.
Ethanolic extract of Hypericum perforatum (HPEE) supplementation in broiler diets did not negatively impact growth performance but improved immune response, reduced abdominal fat, serum AST activity, MDA concentration, cholesterol, LDL, and glucose levels.
Moacir C do Couto Junior, Leandro I da Silva et al.
Nanofertilizers demonstrate potential for enhanced nutrient use efficiency, increased crop yields, and reduced environmental losses compared to conventional fertilizers, but require further research on long-term environmental fate, ecotoxicological effects, and regulatory frameworks for safe and sustainable implementation.
Sylvia Ms Chungchunlam, Paul J Moughan
When nutrient bioavailability was considered, animal-sourced foods, particularly beef meat, were favorably included in cost-minimized, nutrient-adequate diets for the United States population, serving as an economically viable source of essential nutrients.
Hala A Abdelhady, Aya M Yassin et al.
Short-term supplementation with Spirulina platensis (0.04 and 0.08 g/kg) in working dogs modulated biochemical profiles, antioxidant status, inflammatory and immune biomarkers, gut integrity markers, and selected fecal microbiota, with the higher dose showing more pronounced effects.
Takashi Matsunaga, Kazumasa Yamagishi et al.
The combination of H. pylori infection, subsequent atrophic gastritis, and low vitamin B12 intake may be linked to an increased risk of disabling dementia.
Nezihe Otay Lule, Kemal Ozan Lule et al.
Greater adherence to the Mediterranean diet was independently associated with reduced severity of dyspeptic symptoms (pain and non-pain) and increased symptom-related satisfaction in older adults experiencing dyspepsia.
Jun Wen, Xinpeng Wang et al.
Supplementing soybean meal-based diets with 1% or 2% yeast enzyme hydrolysis slurry (YS) improved growth performance, intestinal health, and metabolic responses in juvenile largemouth bass compared to a soybean meal-only diet.
Ali Sassi, Alexandra Chassot et al.
Aldosterone strengthens the collecting duct paracellular sodium barrier by inducing claudin-3, and in its absence, compensatory upregulation of other claudins and sodium transporters preserves sodium homeostasis under low-salt conditions.
Lucia Acampora, Federica Restolfer et al.
The gut-thyroid axis is a bidirectional regulatory network where intestinal barrier integrity, microbiota-driven deconjugation, and micronutrient absorption directly modulate thyroid hormone bioavailability and systemic metabolic homeostasis.
Sâmara V Rocha, Chiara Bernardini et al.
Citrus cystatin (CsinCPI-2) significantly increased mortality in CLas-negative nymphs and both CLas-negative and CLas-positive adults, suggesting its potential as a tool to manage Diaphorina citri and slow Huanglongbing spread.
Natalia S Fanelli, Juliana Cfr Martins et al.
SPHC demonstrated superior protein quality compared to SPHI1 and SPHI2, classifying it as a 'good' quality protein for children (6 months to 3 years) and an 'excellent' quality protein for individuals older than 3 years, while SPHI1 and SPHI2 showed lower protein quality, with processing methods influencing these differences.
Beibei Zhang, Yang Ci et al.
Dietary glutathione supplementation in growing male minks improved crude fat and amino acid digestibility, enhanced antioxidant capacity, and improved intestinal morphology, with an optimal dose of 200 mg/kg.
Bin Wang, Xiaodan Zhang et al.
Supplementation of valine or restriction of isoleucine in low-protein diets alleviates BCAA antagonism by influencing insulin function, with valine inducing insulin resistance and isoleucine promoting insulin secretion.
David Agus Setiawan Wibisono, Chiou-Yeong Saw et al.
*Streptococcus thermophilus* ST4 supplementation significantly increased essential amino acid bioavailability, both in vitro and in vivo, thereby improving the nutritional quality of soy protein.
Wang Yi, Di Wu et al.
The Mapk13-Tcf1-Slc7a5-methionine metabolism axis is critical for maintaining stem-like CD4+ T cells and driving chronic allograft vasculopathy (CAV), and disrupting this axis through genetic deletion, methionine restriction, or Mapk13 inhibition prevents CAV in mouse models.
Nada Alsayari, Ramesa Shafi Bhat et al.
Multi-strain probiotics demonstrated superior efficacy over bee pollen prebiotics in restoring intestinal barrier integrity and suppressing CCl4-induced dysbiosis, specifically by normalizing Zonulin levels and reversing histopathological damage.
Dongchi Cai, Jialin Ji et al.
Branched-chain amino acid (BCAA) metabolic reprogramming is fundamental to cancer biology, influencing tumor growth, immune evasion, and therapy resistance, and targeting these pathways offers a promising therapeutic avenue.
Mequanint Gashew, Gebrehaweria K Reda et al.
Dietary arginine supplementation increased hen-day egg production in adult female Japanese quail without affecting body or egg mass, while arginine restriction downregulated several key metabolic and antioxidant genes.
Xinyue Wang, Zhonghan Xu et al.
Periodontitis promotes colonic inflammation by gut microbiota-induced suppression of the GPR109A receptor, leading to epithelial barrier destruction, and activation of GPR109A restores barrier function and attenuates inflammation.
Ai Takemura, Yutaka Matsunaga et al.
Alpha-ketoglutarate (AKG) supplementation improved non-fasting glucose levels and partially attenuated the decrease in PGC-1α and GLUT4 proteins in adipose tissue of diabetic mice.
Dana Stoian, Denisa Pescari et al.
Elevated circulating trimethylamine N-oxide (TMAO) is associated with cardiometabolic risk factors and complications in both children and adults, potentially reflecting early metabolic alterations in pediatrics and cumulative metabolic burden in adults.
Vicenzo L DeVito, Bhargav R Karamched
The BCAT model, a PK-PD framework integrating probiotic transit, endogenous microbiome metabolism, and enzymatic transformation, achieved a 5% mean prediction error in validating against native microbiome choline metabolism and SYNB1618 clinical trial data, significantly outperforming prior models, and predicts that ~10⁹.⁷ CFU of TMM-expressing probiotic, administered 3–4 hours before meals, achieves a 95% reduction in systemic TMA for TMAU treatment.
Yuxiu Ji, Lijia Zhao et al.
Fecal microbiota transplantation (FMT) shows promise for obesity, but its clinical benefits are transient and variable, necessitating high-quality, large-scale clinical trials to establish standardized protocols and evaluate long-term safety and efficacy before routine clinical application.
Yeni Widiawati, Lisa Praharani et al.
Mixed legume leaf powder supplementation significantly increased nutrient intake and digestibility in female swamp buffaloes but did not significantly affect body weight gain, serum metabolites, or reproductive hormone profiles when animals were already adequately nourished.
Faisal Eudes Sam, Simon Achaglinkame et al.
While research supports the feasibility of incorporating underutilized crops like quinoa, Bambara groundnut, OFSP, and sesame seed into extruded snacks, inconsistent reporting of processing severity and outcome metrics limits comparability and translation.
Amaani Ahmad, Sameera Oruganti et al.
The SARC-F and MSRA-5 questionnaires identified a greater proportion of young adults with Juvenile Idiopathic Arthritis (JIA) experiencing functional difficulties and recurrent falls compared to healthy controls, suggesting their utility in reflecting JIA-related musculoskeletal impairment.
Pengshun Liu, Fan Yang et al.
Dietary L-citrulline supplementation at 30 g/d significantly improved nutrient digestion, nitrogen metabolism, antioxidant capacity, and gut microbiota diversity in late-pregnant Yili mares, with this dosage identified as optimal for overall health.
Sowmya Pujari, Ranjitha S Shetty et al.
Maternal perceptions in the Koraga community, shaped by cultural norms and socioeconomic factors, significantly influence child health and nutrition, with mothers recognizing improved health due to increased healthcare access but also facing barriers like remoteness and caste discrimination.
Ioannis Kosmidis, Christina Karpouzi et al.
Six weeks of high-intensity functional training improved workout duration, shoulder press strength, and core strength endurance, but supplementation with fish protein, vitamin D, and ω3 fatty acids did not enhance these adaptations in recreationally trained individuals.
Monica Manciulea Profir, Luciana Alexandra Pavelescu et al.
The Three-Layer Ecosystem Disruption (TLED) Model demonstrates that ultra-processed food additives, such as emulsifiers and artificial sweeteners, increase chronic disease risk by destabilizing the intestinal mucus barrier, reprogramming microbial metabolism toward pro-inflammatory states, and inducing sustained immune activation across the life course.
Jiujia Liang, Zhihui Luan et al.
Testes-specific protease 50 (TSP50) protects against metabolic dysfunction-associated steatotic liver disease (MASLD) by catalytically degrading stearoyl-CoA desaturase 1 (SCD1), thereby suppressing de novo lipogenesis.
Fayiz M Reda, Ayman S Salah et al.
Dietary black pepper oil supplementation at 0.8% significantly improved growth performance in Japanese quails, leading to increased body weight and weight gain, and a better feed conversion ratio, while also reducing intestinal bacterial counts and improving antioxidant status and lipid profiles.
Caner Özyildirim, Merve Seyda Karaçil Ermumcu et al.
Problematic mealtime behaviours in children with ASD were a strong independent predictor of lower diet quality, and caregivers of girls reported significantly higher stress and burden than caregivers of boys.
Yang Song, Ning Liu et al.
Rumen-unprotected glucose supplementation promotes intramuscular fat deposition and improves meat quality in Xinjiang Brown cattle through volatile fatty acid production and microbial changes.
Wenjing Chen, Yifan Zhao et al.
Barley leaf (BL) supplementation exerts cardioprotective effects against myocardial infarction (MI) by modulating the gut microbiota to enrich Lachnospiraceae, whose derived extracellular vesicles (L-EVs) improve intestinal stem cell function via the ERα-Slc6a14-Hippo signaling pathway, thereby enhancing gut barrier integrity and reducing myocardial injury.
Aubrey K Roberts, Daniel J Panyard et al.
Appendicular lean soft tissue (LST) change was modest after 6 months of diet-based weight loss, with delta homolog 1 (DLK1) emerging as the top protein biomarker linked to LST retention.
Xin Liu, Menghan Chang et al.
The alfalfa transcription factor MsbHLH60 enhances Arabidopsis tolerance to iron deficiency and cadmium toxicity by interacting with MsFIT and boosting its activation of MsIRT1 expression, with Cd tolerance being attenuated by iron deficiency.
Hong Min Shaye Peng, Simone Meiqi Ong et al.
Maternal anemia was highly prevalent (66.2%) in this multi-ethnic Asian cohort, with Indian and Malay mothers showing significantly higher odds of anemia compared to Chinese mothers across all trimesters.
Camelia Munteanu, Revathy Nadhan et al.
Long non-coding RNAs (lncRNAs) act as crucial molecular interfaces that integrate nutritional signals with cancer biology, offering a mechanistic framework for precision cancer chemoprevention by modulating oncogenic and tumor-suppressive pathways.
Huifang Su, Xiandong Liu
In adults with preclinical heart failure, higher CALLY was associated with lower all-cause and cardiovascular mortality, while higher RAR and BAR were associated with higher mortality, with RAR showing the most consistent incremental prognostic value.
Radwa A Hanafy, Kuppan Gokulan et al.
Pretreatment with 10 µg/mL 10 nm AgNPs significantly increased *Salmonella serovar Heidelberg* invasion and intracellular persistence in human intestinal epithelial T84 cells, while also upregulating intestinal permeability-associated genes and altering cytokine profiles, indicating compromised barrier integrity and dysregulated immune function.
Edwin Habeych, Sylvie Merinat et al.
Ferrous picolinate is a promising iron fortificant for polyphenol-rich dairy foods, preserving sensory properties and delivering iron bioaccessibility equivalent to ferrous sulfate.
Eldon O Ager, Colette A Nickodem et al.
Vaccination and iron supplementation interact to significantly alter the beta diversity of the broiler chicken cecal microbiome, with the combination of treatments suppressing beneficial SCFA-producing genera while increasing Staphylococcus.
Umi Fahmida, Min Kyaw Htet et al.
A substantial proportion of pregnant women in East Lombok, Indonesia, experienced high levels of stress (86.3%), depression (26.5%), and common mental disorders (29.7%), with low adherence to healthy diets, iron deficiency, and low social support being significant contributing factors.
Varrsan Dindukurthi, Dhruv Jain et al.
The proposed Graph-RAG framework demonstrated improved ranking consistency, nutrient alignment, reduced nutrient-dominance bias, and enhanced demographic sensitivity for personalized nutrition recommendations compared to baseline models.
Karina L Hissen, Michael F Criscitiello
Dietary L-glutamate supplementation did not improve growth or intestinal morphology in 100 g hybrid striped bass, although a deficiency in dietary glutamate may reduce goblet cell distribution, potentially compromising mucosal immunity.
Einas Abdullah Tahir, Muhtadi G Ahmed et al.
Metformin use in children and adolescents was associated with a 1.4% vitamin B12 deficiency rate in RCTs and 18.7% in observational studies after at least 12 months, with non-statistically significant decreases in vitamin B12 levels observed at 6 and 12 months.
Alex Lang, Sharon Geva et al.
Stroke survivors and their carers experience significant unmet needs regarding personalized, culturally sensitive nutrition information and consistent dietetic support throughout the rehabilitation and recovery pathway, highlighting a need for improved pre-discharge preparation and post-discharge access to resources.
Xiaomei Wang, Huimin Zhao et al.
Research on polyphenols for neurodegenerative diseases has significantly increased since 2000, with China and the US as leading contributors, focusing on oxidative stress, neuroinflammation, and cognition, primarily in Alzheimer's disease, though clinical evidence is limited by bioavailability and trial heterogeneity.
Jifang Zhu, Yiqing Jiang et al.
A higher dietary energy-to-fiber ratio (EFR) was significantly associated with increased odds of poor systolic blood pressure control (OR, 1.008; 95% CI, 1.005–1.011) and diastolic blood pressure control (OR, 1.005; 95% CI, 1.002–1.008) in Chinese patients with essential hypertension.
Bruno Braga Carnino, Ana Ligia Braga Mezzina et al.
Supplementing weaned piglet diets with probiotics and a multienzyme blend, particularly in combination with antibiotics, led to improved performance (higher body weight and average daily gain) and a reduction in belly nosing behavior, with the probiotic and enzyme combination also enhancing nitrogen absorption.
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